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Showing posts with label asbestos-related lung disease. Show all posts
Showing posts with label asbestos-related lung disease. Show all posts

Asbestos Textile Workers Show High Mortality Rates From Occupational Lung Diseases

Saturday, August 8, 2009

A new study by Duke University, in conjunction with the University of Nevada (UNR) and the University of North Carolina, shows that former North Carolina workers employed in asbestos-textile plants have a definitively higher rate of asbestos-related diseases than the population at large.

The study, headed by Dana Loomis, Interim Director, UNR's School of Community Health Sciences, examined 5,770 employees who worked at least one day between January 1, 1950 and December 31, 1973.

The results, which showed that the mortality rate was significantly higher for all causes (1.47 as compared to a value of 1.00 for the general population), also showed that deaths from lung cancer ranked at 1.96 (as compared to a value of 1.00).

The pleura are the membranes that line the inside of the chest cavity and surround the lungs, enabling the lungs to expand to the appropriate degree inside the diaphragm when people breathe. Pleural mesothelioma is a type of pleural cancer caused primarily by asbestos fibers, and is the most common type of mesothelioma.

Asbestos fibers, inhaled, result in irritation of the pleura, or mesothelial lining. Because the body has no way to expel the fibers, the persistent irritation leads to lesions, which in turn lead to cancer.

Pneumoconiosis, the second category of occupational lung diseases, is an interstitial disease, a classic example of which is pulmonary fibrosis. Interstitial diseases affect the walls of the air sacs inside the lungs, rather than the pleural lining over the lungs, and result in scarring. This, in turn, limits a lung's ability to expand properly. Medication can occasionally slow the progress of pneumoconiosis, but many individuals, once affected, never regain the full use of their lungs, and lung transplants are the only option.

Asbestosis is a breathing disorder specifically caused by inhaling asbestos fibers, and is usually a cumulative effect, arising after years of exposure. The fibers cause lung scarring, which can gradually restrict breathing to such an extent that patients are unable to walk more than a few feet without stopping, and require constant oxygen. The symptoms, which can range from mild to severe depending on exposure and a person's general stamina, commonly don't appear until years after exposure to asbestos fibers.

The Duke, UNR study demonstrated a statistical risk across the entire spectrum of 2 to 3 percent higher for each year asbestos fibers were inhaled - figures which were more consistent among white males than for any other group surveyed. The second at-risk category was white females, and both groups scored higher in the risk assessment categories than black males, presumably because the latter group saw fewer smokers and workers who occupied different regions of the asbestos textile plants, namely preparation and carding operations, where fibers were shorter than in the spinning and twisting sections where white males generally worked, according to transmission electron microscopy, or TEM, analyses.

U.S. Environmental Protection Agency regulations (limiting asbestos to 1 percent of product by weight or volume) have driven the asbestos textile industry overseas. This is good news for American workers, but not so good for workers in places like Korea and Egypt, for example.

Attempts by the United Nations to add asbestos to the list of hazardous substances already on the Rotterdam Convention have been consistently opposed by Canada, which is the world's largest supplier of chrysotile asbestos.
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Asbestos Textile Workers Show High Mortality Rates From Occupational Lung Diseases

A new study by Duke University, in conjunction with the University of Nevada (UNR) and the University of North Carolina, shows that former North Carolina workers employed in asbestos-textile plants have a definitively higher rate of asbestos-related diseases than the population at large.

The study, headed by Dana Loomis, Interim Director, UNR's School of Community Health Sciences, examined 5,770 employees who worked at least one day between January 1, 1950 and December 31, 1973.

The results, which showed that the mortality rate was significantly higher for all causes (1.47 as compared to a value of 1.00 for the general population), also showed that deaths from lung cancer ranked at 1.96 (as compared to a value of 1.00).



The pleura are the membranes that line the inside of the chest cavity and surround the lungs, enabling the lungs to expand to the appropriate degree inside the diaphragm when people breathe. Pleural mesothelioma is a type of pleural cancer caused primarily by asbestos fibers, and is the most common type of mesothelioma.

Asbestos fibers, inhaled, result in irritation of the pleura, or mesothelial lining. Because the body has no way to expel the fibers, the persistent irritation leads to lesions, which in turn lead to cancer.

Pneumoconiosis, the second category of occupational lung diseases, is an interstitial disease, a classic example of which is pulmonary fibrosis. Interstitial diseases affect the walls of the air sacs inside the lungs, rather than the pleural lining over the lungs, and result in scarring. This, in turn, limits a lung's ability to expand properly. Medication can occasionally slow the progress of pneumoconiosis, but many individuals, once affected, never regain the full use of their lungs, and lung transplants are the only option.

Asbestosis is a breathing disorder specifically caused by inhaling asbestos fibers, and is usually a cumulative effect, arising after years of exposure. The fibers cause lung scarring, which can gradually restrict breathing to such an extent that patients are unable to walk more than a few feet without stopping, and require constant oxygen. The symptoms, which can range from mild to severe depending on exposure and a person's general stamina, commonly don't appear until years after exposure to asbestos fibers.

The Duke, UNR study demonstrated a statistical risk across the entire spectrum of 2 to 3 percent higher for each year asbestos fibers were inhaled - figures which were more consistent among white males than for any other group surveyed. The second at-risk category was white females, and both groups scored higher in the risk assessment categories than black males, presumably because the latter group saw fewer smokers and workers who occupied different regions of the asbestos textile plants, namely preparation and carding operations, where fibers were shorter than in the spinning and twisting sections where white males generally worked, according to transmission electron microscopy, or TEM, analyses.

U.S. Environmental Protection Agency regulations (limiting asbestos to 1 percent of product by weight or volume) have driven the asbestos textile industry overseas. This is good news for American workers, but not so good for workers in places like Korea and Egypt, for example.

Attempts by the United Nations to add asbestos to the list of hazardous substances already on the Rotterdam Convention have been consistently opposed by Canada, which is the world's largest supplier of chrysotile asbestos.


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Mesothelioma Updates : New Technology To Detect Asbestos-Related Lung Disease

Sunday, July 12, 2009

Michael Harbut, M.D., MPH, co-director of the National Center for Vermiculite and Asbestos-Related Cancers (NCVAC) at the Barbara Ann Karmanos Cancer Institute in Detroit, MI, and chief of the Center for Occupational and Environmental Medicine Wayne State University, announced the use of a new technology to aid in the diagnosis of asbestos-related lung disease. The announcement was made at the Asbestos Disease Awareness Organizations annual conference, Saturday, March 28, in Manhattan Beach, CA.

"Radiographic approaches developed by Carmen Endress, M.D., FACR, Associate Professor of Radiology, Wayne State University School of Medicine and radiologist at the NCVAC, allow us to visualize lesions caused by asbestos exposure in three dimensional detail and often at a much earlier stage than that of the current standard radiographic techniques," said Harbut.

This new approach involves taking images obtained on the 64-slice high resolution CT scan and enhancing them using the Vitrea imaging software program developed by Vital Images, Inc.

Harbut explained, "The benefits of this new approach include the possibility of earlier detection; better differentiation between patients with scarring on the lungs and other diseases; assistance in determining why some people who have thickening on the covering of the lungs have uncontrolled, unrelenting pain; and potentially increased success in the overall diagnosis and treatment of asbestos-related disease.


According to Harbut, this approach could also have a significant public-health impact.

If we can identify the sentinel or first cases of asbestosis or lung cancer at an early stage, then we can help identify asbestos exposures in places where it might not have previously been suspected. Such identification of early detection could help to reduce the death rate from asbestos-related diseases."

Harbut added that this new technology approach to chest radiography could also help reduce cases of fraud which have been reported in asbestos litigation, due to the clarity and sophistication of the images that can help identify which cases are asbestos-related and which are not.

Dr. Endress added, "Its my sincere hope that with this new approach and enhanced technology we will help reduce the death rate caused by asbestos-related diseases, reduce the suffering by patients and their loved ones, and make a significant contribution to medicine."

The use of this technology in the diagnosis and treatment of asbestos-related cancers and high-malignancy potential asbestos-related diseases represents another first for Karmanos Cancer Institute scientists and physicians. Previously, NCVAC researchers were among the first to discover the value of osteopontin a tumor marker of mesothelioma and published this finding in the New England Journal of Medicine. Karmanos workers have also reported the potential value of soluble mesothelin-related peptide, another tumor marker, in screening for mesothelioma.

Michael Harbut, M.D., MPH, Chief of the Center for Occupational and Environmental Medicine, is co-director of the National Center for Vermiculite and Asbestos-Related Cancers at the Barbara Ann Karmanos Cancer Institute, in Detroit, MI. In response to the United States Environmental Protection Agency's (EPA) identification of major sources of public asbestos exposure in Michigan, and to address the need for early diagnosis and aggressive treatment of asbestos-related diseases, the Barbara Ann Karmanos Cancer Institute and the Center for Occupational and Environmental Medicine (COEM) affiliated with Wayne State University, joined forces to establish The National Center for Vermiculite and Asbestos-Related Cancers (NCVAC). COEM has had a long interest in asbestos-related diseases and the Karmanos Cancer Institute is heavily involved in both clinical and basic research on asbestos-related cancers enabling the two centers to rapidly bring together the expertise and resources necessary to study the problem immediately.

Source: Karmanos Cancer Institute
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Scientific And Medical Facts About Chrysotile Asbestos Will Be Presented To US Congress

The Environmental Information Association (EIA) and the Asbestos Disease Awareness Organization (ADAO) today announced the development of the Chrysotile Asbestos Fact Sheet (CAFS). The EIA and ADAO concluded, along with the majority of scientific agencies, that there is sufficient evidence to support that all forms of asbestos, including chrysotile, are carcinogenic and are responsible for asbestos-related lung cancer, mesothelioma, laryngeal and ovarian cancers.

The CAFS provides clear, easily digested information on the dangers of chrysotile, compiled by asbestos medical experts and scientists with a collective 300 plus years of experience and hundreds of peer review scientific publications on asbestos among themselves.

The Chrysotile Asbestos Fact Sheet will be presented to the United States Congress as a scientifically developed paper in support of the continued efforts to ban asbestos. The Environmental Information Association and the Asbestos Disease Awareness Organization continues to educate the public and government representatives to the dangers of asbestos.

"The Environmental Information Association is proud to collaborate with the Asbestos Disease Awareness Organization to produce the EIA/ADAO Chrysotile Asbestos Fact Sheet, in an effort to clarify the misinformation released on the very real dangers of asbestos exposure," said J. Brent Kynoch, Managing Director, Environmental Information Association. "We will continue our endeavor for full acknowledgement by the asbestos industry, and widespread education of the public, of the risks associated with asbestos."

"Somberly, we honor and remember victims today on Worker's Memorial Day who have died from asbestos exposure," said Linda Reinstein, Executive Director, Asbestos Disease Awareness Organization. "Asbestos exposure is the world's leading cause of cancer in the workplace and the United States Congress must act now and ban asbestos. Prevention is our only cure for asbestos-caused diseases."

The contributors of the document include: Michael Breu CIH, Dana Brown, Dr. Ronald Dodson, William Ewin, Joy Finch, Sean Fitzgerald, Dr. Arthur Frank, Steve Hays PE CIH, Dave Hogue, Brent Kynoch, Tom Laubenthal, Dr. Richard Lemen, Dr. James Millette, Linda Reinstein, Andreas Saldivar, and Dr. James Webber.

Source: Asbestos Disease Awareness Organization
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